Risk Assessment of Residual Genomic DNA in Therapeutic Proteins Using Gene Copy Number Application. R Fadnis, R NR, R Soni. Bio Processing Journal 13 (1) (2014).
A new signal sequence for recombinant protein secretion in Pichia pastoris. N Govindappa, M Hanumanthappa, K Venkatarangaiah, S Periyasamy, S Sreenivas, R Soni, K Sastry. J Microbiol Biotechnol 24, 337-45 (2014).
Development of a Novel Reporter Gene Vector for Cell Based Angiogenic Studies. S Kokatam, D Pandey, R Gupta, R Krishna, R Soni. Combinatorial chemistry & high throughput screening 14 (8), 703-709 (2011).
Co-expression of Recombinant Human CYP2C9 with Human Cytochrome P450 Reductase in Protease Deficient S. cerevisiae Strain at a Higher Scale Yields an Enzyme of Higher Specific Activity. K N Purnachandra Rao, S Kumar Suman, Y Ravi Kiran, A Ranjan Kuanr, A K Gupta, K Bhalla, V Kumar, P Kundu, K Arora, R Soni. Drug metabolism letters 4 (4), 246-253 (2010).
Creation of a genetically engineered protease deficient yeast strain having human Cyp450. R Soni, P Gupta. DRUG METABOLISM REVIEWS 41, 50-51 (2009).
Biotech Venture/Setting Up a New Biotech Venture in India. PK Kundu, R Soni JOURNAL OF BIOLAW AND BUSINESS 11 (1), 52-54 (2008).
Gene expression profile of ovalbumin-induced lung inflammation in a murine model of asthma. R Malik, P Priyadarsiny, R Shirumalla, R Soni, A Ray, K Saini. Journal of Investigational Allergology and Clinical Immunology 18 (2), 106 (2008).
Discerning relationships among human cytochrome P450s by computational analyses. A Juneja, KS Saini, R Soni. Bioinf. Trends 1, 1-12 (2006).
Pharmacogenomics: A Step Towards Personalized Medicine. N Mehrotra, R Soni. Bioinformatics India Journal 3 (5) (2005).
A novel and highly divergent Arabidopsis cyclin isolated by complementation in budding yeast. S Abrahams, G Cavet, EA Oakenfull, JP Carmichael, ZH Shah, R Soni, JAH Murray. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1539 (1), 1-6 (2001).
Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4. R Soni, T O'Reilly, P Furet, L Muller, C Stephan, S Zumstein-Mecker, H Fretz, D Fabbro and B Chaudhuri. Journal of the National Cancer Institute 93 (6), 436-446 (2001).
Relevance: Can help us in designing selective specific inhibitors of CDK’s. CDK’s play an important role in cell proliferation and cancer.
Cell cycle arrest mediated by a pyridopyrimidine is not abrogated by over-expression of Bcl-2 and cyclin D1. R Soni, B Chaudhuri. International journal of Oncology 18 (5), 1035-1040 (2001).
Novel CDK inhibitors restore TGF-β sensitivity in CDK4 overexpressing epithelial cells. R Soni, H Fretz, L Muller, J Schoepfer, B Chaudhuri. Biochemical and biophysical research communications 272 (3), 794-800 (2000).
Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product. R Soni, L Muller, P Furet, J Schoepfer, C Stephan, S Zumstein-Mecker, H.Fretz and B Chaudhuri. Biochemical and biophysical research communications 275 (3), 877-884 (2000).
Plant D cyclins and retinoblastoma (Rb) plant homologues. JAH Murray, D Freeman, J Greenwood, R Huntley, J Makkerh, C Riou-Kharnlichi, D A Sorrell, C Cockcroft, JP Carmichael, R Soni. PORTLAND PRESS RESEARCH MONOGRAPH, 99-128 (1998).
Modulation of cyclin transcript levels in cultured cells of Arabidopsis thaliana. RAUA Fuerst, R Soni, JAH Murray, K Lindsey. Plant Physiology 112 (3), 1023-1033 (1996).
A family of cyclin D homologs from plants differentially controlled by growth regulators and containing the conserved retinoblastoma protein interaction motif. R Soni, JP Carmichael, ZH Shah, JA Murray. The Plant Cell 7 (1), 85-103 (1995).
Relevance: Suggests conservation of cell cycle machinery across eukaryotes and help in understanding plant cell growth and development. Will help to address the issue of the control of cell proliferation in plant systems.
Isolation of intact DNA and RNA from plant tissues. R Soni, JAH Murray. Analytical biochemistry 218 (2), 47 (1994).
Parameters affecting lithium acetate-mediated transformation of Saccharomyces cerevisiae and development of a rapid and simplified procedure. R Soni, JP Carmichael, JAH Murray. Current genetics 24 (5), 455-459 (1993).
A rapid and inexpensive method for isolation of shuttle vector DNA from yeast for the transformation of E. coli. R Soni, JA Murray. Nucleic acids research 20 (21), 5852 (1992).